A Nonsense Variant in COL6A1 in Landseer Dogs with Muscular Dystrophy
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چکیده
منابع مشابه
A Nonsense Variant in COL6A1 in Landseer Dogs with Muscular Dystrophy
A novel canine muscular dystrophy in Landseer dogs was observed. We had access to five affected dogs from two litters. The clinical signs started at a few weeks of age, and the severe progressive muscle weakness led to euthanasia between 5 and 15 months of age. The pedigrees of the affected dogs suggested a monogenic autosomal-recessive inheritance of the trait. Linkage and homozygosity mapping...
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ژورنال
عنوان ژورنال: G3 Genes|Genomes|Genetics
سال: 2015
ISSN: 2160-1836
DOI: 10.1534/g3.115.021923